Original research••

Impact of COVID-19 on recorded blood pressure screening and hypertension management in England: an analysis of monthly changes in the quality and outcomes framework indicators in OpenSAFELY

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Abstract

Background The COVID-19 pandemic disrupted cardiovascular disease management in primary care in England.

Objective To describe the impact of the pandemic on blood pressure screening and hypertension management based on a national quality of care scheme (Quality and Outcomes Framework, QOF) across key demographic, regional and clinical subgroups.

Methods With NHS England approval, a population-based cohort study was conducted using OpenSAFELY-TPP on 25.2 million NHS patients registered at general practices (March 2019 to March 2023). We examined monthly changes in recorded blood pressure screening in the preceding 5 years in patients aged ≥45 years and recorded the hypertension prevalence and the percentage of patients treated to target (≤140/90 mmHg for patients aged ≤79 years and ≤150/90 mmHg for patients aged ≥80 years) in the preceding 12 months.

Results The percentage of patients aged ≥45 years who had blood pressure screening recorded in the preceding 5 years decreased from 90% (March 2019) to 85% (March 2023). Recorded hypertension prevalence was relatively stable at 15% throughout the study period. The percentage of patients with a record of hypertension treated to target in the preceding 12 months reduced from a maximum of 71% (March 2020) to a minimum of 47% (February 2021) in patients aged ≤79 years and from 85% (March 2020) to a minimum of 58% (February 2021) in patients aged ≥80 years before recovery. Blood pressure screening rates in the preceding 5 years remained stable in older people, patients with recorded learning disability or care home status.

Conclusions The pandemic substantially disrupted hypertension management QOF indicators, which is likely attributable to general reductions of blood pressure measurement including screening. OpenSAFELY can be used to continuously monitor changes in national quality-of-care schemes to identify changes in key clinical subgroups early and support prioritisation of recovery from care disrupted by COVID-19.

What is already known on this topic

The COVID-19 pandemic disrupted cardiovascular disease management in primary care in England.

What this study adds

We have reported monthly QOF outcomes for blood pressure monitoring and hypertension control across key demographic, regional and clinical subgroups during the COVID-19 pandemic.
We have translated the QOF business rules for blood pressure monitoring and hypertension control from text descriptions into a reusable and modifiable code.

How this study might affect research, practice or policy

The OpenSAFELY platform could be used to report current and future indicators of clinical care and to identify health inequalities among regional, demographic or clinical sub-populations in near real-time.

Introduction

The COVID-19 pandemic disrupted healthcare services globally.1 Cardiovascular disease (CVD) management in primary care in England was impacted2–4 with an estimated 2175 non-COVID excess deaths attributed to hypertensive diseases between March 2020 and December 2021.5 CVD is associated with a higher risk of morbidity and mortality from COVID-19, emphasising the importance of maintaining good routine care.6 7 High blood pressure is the leading risk factor for CVD8 and one of the top three risk factors for global disease burden.9 Since 1994, there has been an improvement in the management of high blood pressure in England10 and a reduction of the negative impact of social deprivation on blood pressure management.11 Delayed management of hypertension is associated with worse clinical outcomes, for example, stroke.12 Recent results from annual national audits of England’s population on CVD have also suggested that blood pressure management was disrupted by the pandemic.13

In 2004, the Quality and Outcomes Framework (QOF) was introduced in England as one of the largest initiatives worldwide to improve the quality of care in general practice. General practitioners (GPs) and their staff are measured on indicators of good clinical care and receive financial incentives based on their achievement of certain thresholds.14 15 To monitor the indicators and thresholds, NHS Digital publishes text descriptions of analytic rules and logic, commonly referred to as ‘business rules’, which are taken by software providers and implemented in GP electronic health record systems. GPs can review their delivery of care against these rules and indicators for their practice throughout the financial year; however, national data for all practices are only available annually. At the end of every NHS financial year on March 31, NHS Digital calculates each practice’s achievement against set thresholds for individual indicators. Between 1 April 2020 and 31 March 2023, amendments were made to QOF, and some preventative indicators were suspended, including hypertension management, to support the COVID-19 response and support roll out of the national COVID-19 vaccination programme.16 17

OpenSAFELY is a secure analytics platform for electronic patient records built by our group on behalf of NHS England to deliver urgent academic6 and operational research2 during the pandemic. Using OpenSAFELY-TPP, we therefore aimed to describe trends and variations in these indicators before and during the COVID-19 pandemic and assess recovery of the indicators to pre-pandemic levels across key clinical and demographic subgroups.

Methods

Data source

Primary care records managed by the GP software provider TPP were accessed through OpenSAFELY (https://opensafely.org). OpenSAFELY is a secure analytics platform for electronic patient records built by our group with the approval of NHS England to deliver urgent academic6 and operational NHS service research2 on the direct and indirect impacts of the pandemic.

OpenSAFELY provides a secure software interface allowing the analysis of pseudonymised primary care patient records from England in near real-time within the EHR vendor’s highly secure data centre, avoiding the need for large volumes of potentially disclosive pseudonymised patient data to be transferred off-site. The dataset analysed within OpenSAFELY is based on 25 million people currently registered with GP surgeries using TPP SystmOne software. It includes pseudonymised data such as coded diagnoses, medications and physiological parameters. No free text data are included. Further details on our information governance and ethics can be found in the in the online supplemental file 1.

Study design and population

We conducted a retrospective cohort study from March 2019 to March 2023 using primary care EHR data from all GP practices in England supplied by the EHR vendor TPP, a cohort that is broadly representative of the population in England.18 Following the QOF business rules, we included all patients who were alive and registered with an OpenSAFELY-TPP practice for the QOF hypertension prevalence and management indicators (HYP001, HYP003, HYP007). For the QOF blood pressure screening indicator (BP002), we included only those aged ≥45 years.

Implementation of QOF business rules in analytic code

QOF indicators for blood pressure screening in the preceding 5 years (BP002), hypertension register (HYP001) and hypertension management in the preceding 12 months (HYP003, HYP007) were specified in analytic code replicating the QOF business rules for 2021/22 (Version 46)19 using the OpenSAFELY framework (table 1). All QOF indicators are formed by specifying rules and logic, which determine aggregate counts of patients. Percentages are then calculated using numerator and denominator pairs. In addition to QOF indicators, we also applied the same clinical rules for blood pressure screening (BP002) to all patients with a record of an unresolved hypertension diagnosis using a 12-month lookback period to match the timeframe used in the hypertension management indicators (HYP003 and HYP007).

Table 1

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Descriptions of the Quality and Outcomes Framework indicators for blood pressure (BP) and hypertension (HYP)

Higher indicator percentages represent a higher percentage of patients receiving indicated clinical care. Patients can be excluded from the denominator according to QOF rules, such as those who declined treatment (for more details, see online supplemental tables 1–4. For the two hypertension control indicators (HYP003 and HYP007), patients with hypertension who did not have their blood pressure recorded in the last year are counted as not being treated to target as per the QOF business rules.

Data were analysed for each month between 1 March 2019 and 31 March 2023 covering five financial years. Each monthly cohort replicated the yearly reporting of each QOF business rule. Thus, the data presented for each March in this study align with the reporting period of the corresponding annual QOF reports published by NHS Digital.

Monthly changes in QOF indicators across demographic, regional and clinical subgroups

Trends and variations in QOF indicators were reported across demographic (10-year age bands, sex, ethnicity in 5 and 16 categories), regional (practice level deciles, Indices of Multiple Deprivation quintiles derived from patient’s postcode at lower super output area, region) and key clinical subgroups (record of learning disability and care home status) highlighted in the NHS long-term plan as priority groups.20

Software and reproducibility

Data management and analyses were performed using the OpenSAFELY software libraries with Python (Version 3.8.10) and R (Version 4.0.2). Codes replicating the QOF business rules are available at https://github.com/opensafely/hypertension-sro and https://github.com/opensafely/blood-pressure alongside all analytic code and codelists. The GitHub repository https://github.com/opensafely/qof-utilities contains reusable code developed for implementing QOF rules in OpenSAFELY.

Patient and public involvement

For transparency purposes, we have developed a public website (https://opensafely.org/) that provides a detailed description of the platform in language suitable for a lay audience; we have participated in two citizen juries exploring public trust in OpenSAFELY.21 To ensure the patient voice is represented, we are working closely with appropriate medical research charities; however, there was no patient or public involvement in this specific research question.

Results

Calculating monthly trends in QOF indicators

Detailed demographic characteristics of all patients considered for the blood pressure (n=11 195 670) and hypertension indicators (n=25 287 730) during the reporting period of the NHS financial year 21/22 are presented in table 2.

Table 2

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Cohort description for patients included in the blood pressure and hypertension Quality and Outcomes Framework indicators in OpenSAFELY-TPP during the NHS financial year 21/22

Changes in blood pressure screening and hypertension management rates in the total population

In the total population, the percentage of patients aged ≥45 years (BP002) with recorded blood pressure in the preceding 5 years decreased steadily from its maximum of 90.4% in March 2019 to a minimum of 87.2% in March 2023 (figure 1A).

Figure 1

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Monthly trends from March 2019 to March 2023 in (A) the percentage of patients aged ≥45 years with blood pressure screening in the preceding 5 years (BP002); (B) the hypertension register (HYP001); (C) the percentage of patients diagnosed with hypertension and recorded blood pressure in the preceding 12 months. Demographic, regional and clinical subgroups for panel C are presented in online supplemental figure 2); (D) the percentage of patients diagnosed with hypertension and treated to target (HYP003 and HYP007) in the preceding 12 months. BP, Blood pressure; HYP, Hypertension. The end of the NHS financial years (March) is highlighted with orange dashed vertical lines. Counts of patients in the numerator and denominator pair are presented in online supplemental figures 1C and 2C).

Recorded hypertension prevalence (HYP001) was relatively stable throughout the entire study period (14.7% in March 2019 to 14.9% in March 2023, figure 1B). Blood pressure screening in the preceding 12 months in patients identified as having hypertension decreased from its peak of 88% in March 2019 to its lowest value of 68% in April 2021 and subsequently improved steadily to 85% in March 2023.

Of those aged ≤79 years identified as having hypertension, the percentage of patients with blood pressure treated to target (HYP003) varied from 67.5% in March 2019 to 70.1% in March 2023, with a peak of 70.6% in March 2020 and a lowest value of 47.2% in February 2021 (figure 1C). Of those aged ≥80 years, the percentage of patients with blood pressure treated to target (HYP007) reduced from 85.3% in March 2019 (the peak value) to 79.9% in March 2023, with a lowest value of 57.8% in February 2021 (figure 1D). For both hypertension management indicators (HYP003 and HYP007) as well as blood pressure screening in patients identified as having hypertension, the results indicated a steady improvement between March 2021 and March 2023.

By March 2023, the differences compared with March 2019 were a 3.1% decrease (90.4% to 87.2%) in patients aged ≥45 years (BP002) with recorded blood pressure in the preceding 5 years, a 0.2% increase (14.7% to 14.9%) in recorded hypertension prevalence (HYP001), a 2.6% increase (67.5% to 70.1%), and a 5.4% decrease (85.3% to 79.9%) in patients identified as having hypertension with blood pressure treated to target aged ≤79 and ≥80 years, respectively (HYP003 and HYP007). Counts of patients in the numerator and denominator are presented in online supplemental figure 1.

Changes in blood pressure screening and hypertension management rates in demographic, regional and clinical subgroups

Subgroups for blood pressure screening in the preceding 5 years in patients aged ≥45 years (BP002)

Figure 2 shows the trends in subgroups for blood pressure screening in the preceding 5 years in patients aged ≥45 years (BP002). Preexisting differences in blood pressure screening rates between younger and older age groups increased over the study period, with a reduction in screening observed in younger adults (eg, for age category 45 to 49: 81.9% in March 2019 to 74.9% in March 2023) but not older adults (blood pressure screening was preserved at around 97% in adults aged 80+, figure 2C). Blood pressure screening was also maintained in those with a record of care home status (99.2% in March 2019 to 98.7% in March 2023) or learning disability (98.0% in March 2019 to 98.3% in March 2023, figure 2G,H). From December 2022 to March 2023, results indicate an improvement in recorded blood pressure screening across all demographic and clinical subgroups.

Figure 2

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Monthly, unstandardised trends from March 2019 to March 2023 in the percentage of patients aged ≥45 years with recorded blood pressure in the preceding 5 years in (BP002) broken down by (A) practice level deciles, (B) sex, (C) age band, (D) region, (E) ethnicity, (F) IMD, Indices of Multiple Deprivation, (G) learning disability and (H) care home status for hypertension. The end of the NHS financial years (March) is highlighted with orange dashed vertical lines.

Subgroups for hypertension prevalence (HYP001)

Grouping by demographic subgroups revealed pre-pandemic differences in hypertension recording (figure 3). In March 2019, the national median by practice was 15.0%; however, this was considerably lower in London (10.4%) and in those with an ethnicity record of ‘Mixed’ (6.1%) or ‘Chinese or Other Ethnic Groups’ (6.9%). Hypertension was also less frequently recorded in those living in the most deprived areas (12.8%) compared with those living in the least deprived areas (15.6%). Hypertension was more often recorded in those living in care homes (48.8%) and less frequently in those with learning difficulties (9.6%). The differences observed at pre-pandemic remained similar throughout the study period across most subgroups (figure 3).

Figure 3

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Monthly, unstandardised trends from March 2019 to March 2023 in hypertension prevalence (HYP001) broken down by (A) practice level deciles, (B) sex, (C) age band, (D) region, (E) ethnicity, (F) IMD, Indices of Multiple Deprivation, (G) learning disability and (H) care home status for hypertension. The end of the NHS financial years (March) is highlighted with orange dashed vertical lines. Note that the range of the y-axis varies by breakdown category to highlight differences between groups.

Subgroups for hypertension management in the preceding 12 months in patients aged ≤79 (HYP003) and ≥80 (HYP007) years

Figures 4 and 5 show the trends in subgroups for hypertension management. Preexisting regional differences between subgroups in blood pressure management in patients diagnosed with hypertension aged ≤79 years (HYP003) increased during the study period (figure 4A). In March 2021, the regions South-East and West Midlands had the lowest proportion of patients treated to target, with 39.4% and 41.8%, respectively (figure 5A), compared with the national median by practice of 49.4% and other regions. A similar trend was observed for patients aged ≥80 years (HYP007, figures 4B and 5B).

Figure 4

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Monthly, unstandardised trends from March 2019 to March 2023 in the percentage of patients diagnosed with hypertension treated to target in the preceding 12 months aged ≤79 years (HYP003) and ≥80 years (HYP007) broken down by (A, B) practice level deciles, (C, D) sex, (E, F) age band and (G, H) ethnicity. The end of the NHS financial years (March) is highlighted with orange dashed vertical lines.

Figure 5

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Monthly, unstandardised trends from March 2019 to March 2023 in the percentage of patients diagnosed with hypertension treated to target in the preceding 12 months aged ≤79 years (HYP003) and ≥80 years (HYP007) broken down by (A, B) region, (C, D) IMD, Indices of Multiple Deprivation, (E, F) record of learning disability and (G, H) care home status. The end of the NHS financial years (March) is highlighted with orange dashed vertical lines.

Later in the analysis period, between March 2021 and March 2023, a higher proportion of patients in older age groups (60–69 and 70–79 years) were reported as having their hypertension treated to target than younger age groups.

Between March 2020 and March 2021, the proportion of patients in care homes with hypertension treated to target reduced by 17.4% in those aged ≤79 years (HYP003) and by 18.6% in those aged ≥80 years (HYP007). In March 2023, the proportion of patients with hypertension treated to target had nearly returned to pre-pandemic levels.

Discussion

Summary

These results suggested that the pandemic had a substantial impact on the percentage of patients in whom hypertension was classified as not treated to target within the preceding 12 months. Our analyses suggest that this may be attributed to a reduction in blood pressure measurement in the preceding 12 months. We did not observe a substantial impact of the pandemic on the public health QOF standard for blood pressure screening, which is assessed within the preceding 5 years, or on the register for hypertension prevalence.

Strengths and limitations

This study has a range of strengths. The OpenSAFELY-TPP platform runs analyses across the full raw, pseudonymised, dataset for 25.2 million patients at 2540 practices in England using TPP software. In this study, we have reported monthly QOF measures in near real-time.

We acknowledge several limitations in our analyses. Results within regional and demographic subgroups need to be interpreted carefully because we report unstandardised results and did not account for sociodemographic factors (eg, age differences between subgroups). A recent study found that OpenSAFELY-TPP was largely representative of the general population of England in terms of IMD, age, sex, ethnicity and causes of death, although with relative underrepresentation of practices in London.17

We have implemented QOF business rules as described in the text description published by NHS Digital; however, we would expect our ascertainment of specific patients to deviate from other sources of QOF data for two reasons: (1) as described above OpenSAFELY-TPP has access to the full raw GP record, which many not be the case for all other sources of QOF data; and (2) when translating information from the QOF business rules we had to make pragmatic decisions to resolve some ambiguity.

Finally, we also note that our data will only include clinical codes for blood pressure recording that were carried out in primary care, by a patient at home and correctly captured in a GP system or in secondary care and returned to GPs as structured data. In this study, where blood pressure results are not recorded or correctly captured within a GP system, individuals were counted as not being treated to target, which is consistent with the QOF business rules. The correct capture of clinical coding is a limitation of all EHR analytic work.

Findings in context

Blood pressure screening and hypertension management are national priorities22 as a modifiable strong risk factor for CVD globally.23 Hypertension management has been incentivised by QOF for primary care since 2005, and advances in the detection and management of patients with hypertension have been gradually observed.10 This progression was disrupted by the COVID-19 pandemic. In response to the unparalleled pressure on the health service in the pandemic, some QOF indicators were suspended, including hypertension management in order to support prioritisation of clinical workload.24 Practices may have rightly deprioritised some care described here to focus on more urgent care needs during the COVID-19 pandemic.

We have reported a prevalence of hypertension that is consistent with the latest available official annual report by NHS Digital covering NHS financial year 2021/22 (see online supplemental table 6) and with the second annual audit from the CVDPREVENT initiative (covering data up to March 2021) in England.13 Furthermore, our results are consistent with the most recent quarterly data published by CVDPREVENT including data up to June 2022.25 A consistent finding across our work, CVDPREVENT and official QOF publications was the reduction in the proportion of patients with hypertension treated to target in March 2020 and March 2021; however, our study reveals continued recovery of care beyond this period, particularly during the first months of 2023. CVDPREVENT also reported a reduction of 21.4% in the proportion of patients recorded as having their blood pressure treated and meeting the NICE guideline target between March 2020 and March 2021.13 It is likely that the combination of the factors contributed to this observation. Those without a blood pressure recording in the preceding 12 months were reported as not having their hypertension treated to target (see online supplemental figure 2). This finding is likely due to a 42% reduction of recorded blood pressure measurement activity between April 2019 and April 2021.3 Furthermore, services may have re-prioritised those with poorly controlled blood pressure during the pandemic.

Interestingly, there is a sex- and age-dependent difference in the proportion of patients with hypertension treated to target. The proportion of female patients with hypertension treated to target was consistently greater than male patients aged ≤79 years (figure 4C). However, in patients ≥80 years, this is reversed, with a greater proportion of male patients having their hypertension treated to target (figure 4D). The cause of this trend is beyond the scope of this study, but similar patterns have been observed elsewhere.26 Similarly, the unstandardised results suggest that there is a trend towards a lower proportion of black ethnic patients with hypertension treated to target (figure 4G,H); however, this is likely influenced by age differences between ethnicity groups. Variation in hypertension control according to ethnicity has been described widely elsewhere and the cause of which is likely to be multi-faceted.27

Implications for policy and future research

It is possible that the observed results represent prioritisation of other clinical areas, and the results of this study should not be interpreted as criticism of GPs. The issue has already been recognised, and new NHS services were rapidly established in response (eg, NHS Community Pharmacy Blood Pressure Check Service and BP@home Service).22 28

In this study, we observed that patients from the most deprived areas had the lowest proportion of patients on the hypertension register (HYP001), and this decreased further during the pandemic (figure 3F). There was also a trend towards a lower proportion of black ethnic patients with hypertension treated to target, which has also been observed prior to the pandemic in other elements of CVD care.29 Future research is needed to help understand the reasons for the observed reductions in hypertension management and to further understand the health inequalities to find effective solutions to best address them. The Core20PLUS5, a national NHS England approach to support the reduction of health inequalities at both national and system level, is a new well-placed initiative designed to tackle the management of high blood pressure in these important patient groups.

The OpenSAFELY platform could be used to analyse NHS England, National Institute of Clinical Excellence and Care Quality Commission on current indicators of clinical care and has the technical ability to prototype new ones. The additional demographic and clinical data securely accessible through the OpenSAFELY tools also has a number of advantages to current published reports of QOF. It can be used to identify health inequalities among regional, demographic or clinical sub-populations (eg, ethnicity or record of learning disability) in near real-time for new policies and clinical recommendations. Further, all code used in OpenSAFELY is reusable and modifiable and is available under open source licences, which provides opportunities for a more transparent future for operational analysis in the NHS and research using EHR data.

Conclusion

Although hypertension management indicators were disrupted substantially during the pandemic, this can likely be attributed to a general reduction of blood pressure measurement. Reassuringly, hypertension management indicators have been improving steadily since March 2021 and are now approaching those seen pre-pandemic. While resources were stretched during the pandemic, blood pressure screening was prioritised by GPs in older age groups and patients with a record of learning disability or care home status. OpenSAFELY can be used to continuously monitor monthly changes in quality of care indicators to identify significant changes in key clinical subgroups early.

Supplementary PDF

X: @DarthCTR
Contributors: MW, VS, CC, RH, BG and BM conceptualised the study. MW, VS, CC, RH, HJC, CA, LF, LH, RMS, PI, DE, SM, ID, AJW, JM, AM, SB, CB, JC, JP, FH and SH curated the data. MW, VS, CC, RH, HJC, CA, LF and LH did formal analysis.BG acquired funding. MW, VS, CC, RH, HJC, CA, LF, LH, CTR, VM, LT, CM, MS, AG, CW, ADB, JM and CW did the investigation. MW, VS, CC, RH, HJC, CA, LF and LH created the method. MW, VS, CC, RH and HJC used the software. BG and BMK provided the supervision. MW, VS, CC and RH provided visualisation. MW, VS, CC and RH wrote the original draft. MW, VS, CC, RH, BMK, CTR, VM, LT, CM, MS, AG, CW, ADB, JM, CW, RMS, PI, DE, SM, ID, AJW, JM, AM and SB wrote the review and provided edits. BMK is the guarantor.
Funding: BG’s work on better use of data in healthcare more broadly is currently funded in part by the Wellcome Trust, NIHR Oxford Biomedical Research Centre, NIHR Applied Research Collaboration Oxford and Thames Valley, the Mohn-Westlake Foundation; all DataLab staff are supported by BG’s grants on this work. BMK is also employed by NHS England working on medicines policy and clinical lead for primary care medicines data. RJM is supported by NIHR Oxford and Thames Valley Applied Research Consortium and is an NIHR Senior Investigator. The views expressed are those of the authors and not necessarily those of the NIHR, NHS England, Public Health England or the Department of Health and Social Care. The views expressed are those of the authors and not necessarily those of the NIHR, NHS England, Public Health England or the Department of Health and Social Care. Funders had no role in the study design, collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication.
Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare the following: BG has received research funding from the Laura and John Arnold Foundation, the NHS National Institute for Health Research (NIHR), the NIHR School of Primary Care Research, the NIHR Oxford Biomedical Research Centre, the Mohn-Westlake Foundation, NIHR Applied Research Collaboration Oxford and Thames Valley, the Wellcome Trust, the Good Thinking Foundation, Health Data Research UK, the Health Foundation, the World Health Organisation, UKRI, Asthma UK, the British Lung Foundation and the Longitudinal Health and Wellbeing strand of the National Core Studies programme; he also receives personal income from speaking and writing for lay audiences on the misuse of science.
Provenance and peer review: Not commissioned; externally peer reviewed.
Supplemental material: This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.

Data availability statement

All data were linked, stored and analysed securely within the OpenSAFELY platform (https://opensafely.org/). Data include pseudonymised data such as coded diagnoses, drugs and physiological parameters. No free text data were included. All code is shared openly for review and reuse under MIT open license (https://github.com/opensafely/blood-pressure-sro and https://github.com/opensafely/hypertension-sro). Detailed pseudonymised patient data are potentially re-identifiable and therefore not shared.

Ethics statements

Patient consent for publication:

Ethics approval:

This study was approved by the Health Research Authority (REC reference 20/LO/0651) and by the LSHTM Ethics Board (reference 21863).

Acknowledgements

We are very grateful for all the support received from the TPP Technical Operations team throughout this work and for generous assistance from the information governance and database teams at NHS England and the NHS England Transformation Directorate.

Moynihan R, Sanders S, Michaleff ZA, et al. Impact of COVID-19 pandemic on utilisation of healthcare services: a systematic review. BMJ Open 2021; 11.
doi:10.1136/bmjopen-2020-045343•Google Scholar
Curtis HJ, MacKenna B, Wiedemann M, et al. OpenSAFELY NHS service restoration Observatory 2: changes in primary care activity across six clinical areas during the COVID-19 pandemic. Br J Gen Pract 2023; 73:e318–31.
doi:10.3399/BJGP.2022.0301•Google Scholar
Fisher L, Curtis HJ, Croker R, et al. Eleven key measures for monitoring general practice clinical activity during COVID-19 using federated analytics on 48 million adults’ primary care records through OpenSAFELY. Primary Care Research 2022;
doi:10.1101/2022.10.17.22281058•Google Scholar
Dale CE, Takhar R, Carragher R, et al. The impact of the COVID-19 pandemic on cardiovascular disease prevention and management. Nat Med 2023; 29:219–25.
doi:10.1038/s41591-022-02158-7•Google Scholar
Office for National Statistics. Excess deaths in England and Wales. 2022;
Available: here [Accessed 07 Jul 2022]
Google Scholar
Williamson EJ, Walker AJ, Bhaskaran K, et al. Factors associated with COVID-19-related death using OpenSAFELY. Nature New Biol 2020; 584:430–6.
doi:10.1038/s41586-020-2521-4•Google Scholar
Silverio A, Di Maio M, Citro R, et al. Cardiovascular risk factors and mortality in hospitalized patients with COVID-19: systematic review and meta-analysis of 45 studies and 18,300 patients. BMC Cardiovasc Disord 2021; 21.
doi:10.1186/s12872-020-01816-3•Google Scholar
Fuchs FD, Whelton PK. High blood pressure and cardiovascular disease. Hypertension 2020; 75:285–92.
doi:10.1161/HYPERTENSIONAHA.119.14240•Google Scholar
Lim SS, Vos T, Flaxman AD, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the global burden of disease study 2010. Lancet 2012; 380:2224–60.
doi:10.1016/S0140-6736(12)61766-8•Google Scholar
Falaschetti E, Mindell J, Knott C, et al. Hypertension management in England: a serial cross-sectional study from 1994 to 2011. Lancet 2014; 383:1912–9.
doi:10.1016/S0140-6736(14)60688-7•Google Scholar
Ashworth M, Medina J, Morgan M, et al. Effect of social deprivation on blood pressure monitoring and control in England: a survey of data from the quality and outcomes framework. BMJ 2008; 337.
doi:10.1136/bmj.a2030•Google Scholar
Xu W, Goldberg SI, Shubina M, et al. Optimal systolic blood pressure target, time to intensification, and time to follow-up in treatment of hypertension: population based retrospective cohort study. BMJ 2015; 350.
doi:10.1136/bmj.h158•Google Scholar
Office for Health Improvement & Disparities. CVDPREVENT second annual audit - using data to drive cardiovascular disease prevention. 2021;
Google Scholar
National Institute for Health and Care Excellence. Hypertension in adults: diagnosis and management, NICE. 2019;
Available: here [Accessed 24 Jun 2022]
Google Scholar
NHS Digital. Quality and outcomes framework, 2020-21. 2021;
Available: here [Accessed 12 Apr 2022]
Google Scholar
NHS England. JCVI advice in response to the emergence of the B.1.1.529 (Omicron) variant: next steps for deployment. 2022;
Available: here [Accessed 16 Aug 2022]
Google Scholar
NHS England and NHS Improvement. Update on quality outcomes framework changes for 2022/23. 2022;
Available: here
Google Scholar
Andrews C, Schultze A, Curtis H, et al. OpenSAFELY: representativeness of electronic health record platform OpenSAFELY-TPP data compared to the population of England. Wellcome Open Res 2022; 7.
doi:10.12688/wellcomeopenres.18010.1•Google Scholar
NHS Digital. Quality and outcomes framework (QOF) business rules V46.0 2021-2022 baseline release. 2021;
Available: here [Accessed 20 Jul 2022]
Google Scholar
NHS. The NHS long term plan. 2019;
Available: here [Accessed 28 Jul 2021]
Google Scholar
Oswald M, Laverty L. Data sharing in a pandemic: three citizens’ juries – juries report. 2021;
Available: here
Google Scholar
NHS England. Case study: NHS community Pharmacy blood pressure check service. 2021;
Available: here [Accessed 07 Jul 2022]
Google Scholar
Yusuf S, Joseph P, Rangarajan S, et al. Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study. Lancet 2020; 395:795–808.
doi:10.1016/S0140-6736(19)32008-2•Google Scholar
NHS England. Temporary GP contract changes to support COVID-19 vaccination programme. 2021;
Available: here [Accessed 19 Jul 2022]
Google Scholar
NHS Benchmarking Network. CVDPREVENT quarterly reporting now available, NHS Benchmarking Network. 2022;
Available: here [Accessed 25 Jan 2023]
Google Scholar
NHS England. Report of the review of the quality and outcomes framework in England. 2018;
Available: here [Accessed 19 Jul 2022]
Google Scholar
Marshall IJ, Wolfe CDA, McKevitt C, et al. Lay perspectives on hypertension and drug adherence: systematic review of qualitative research. BMJ 2012; 345.
doi:10.1136/bmj.e3953•Google Scholar
NHS England. Home blood pressure monitoring. 2021;
Available: here [Accessed 15 Jun 2023]
Google Scholar
Eastwood SV, Mathur R, Sattar N, et al. Ethnic differences in guideline-indicated statin initiation for people with type 2 diabetes in UK primary care, 2006–2019: a cohort study. PLOS Med 2021; 18.
doi:10.1371/journal.pmed.1003672•Google Scholar